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. 2022 Nov 16;2(11):e0000438. doi: 10.1371/journal.pgph.0000438

Table 2. Frequency of participants’ reported adverse physical effects (n = 8,216).

Total sample (8,216) Single ayahuasca use participants (598)
n % n (%)
Adverse physical effect 1 , 2 5,742 (69.9) 334 (55.9)
General symptom adverse effect 1 , 3 5,603 (68.2) 321 (53.7)
    Vomiting/nausea 5,097 (62.0) 281 (47.0)
    Headache 1,460 (17.8) 57 (9.5)
    Abdominal pain 1,052 (12.8) 31 (5.2)
    Breathing difficulties 599 (7.3) 33 (5.5)
    Chest pains 384 (4.7) 14 (2.3)
Arthromyalgical adverse effect 1 , 4 883 (10.7) 39 (6.5)
    Aching muscles 617 (7.5) 29 (4.8)
    Coughing/wheezing 273 (3.3) 5 (0.8)
    Stiff/swollen joints 182 (2.2) 12 (2.0)
Neurological adverse effect 1 , 5 416 (5.1) 20 (3.3)
    Fainting 335 (4.1) 13 (2.2)
    Fits or seizures 106 (1.3) 7 (1.2)

1 Reported presence of some of the adverse physical effects studied

2 adverse physical effects range (0–10) and median (1.0)

3 adverse psychophisical effects range (0–5) and median (1.0)

4 adverse arthromyalgic effects range (0–3) and median (0.0)

5 adverse neurological effects range (0–2) and median (0.0).