Table 6. History of ayahuasca use and medical status variables’ relationship with adverse mental health effects for each factor.
| β | p | OR | OR (95% C.I.) | ||
|---|---|---|---|---|---|
| Adverse mental health effects | |||||
| Age of initial use | .012 | .08 | 1.01 | 1.00 | 1.02 |
| Doses/year | .009 | .89 | 1.01 | .89 | 1.14 |
| Lifetime use | .027 | .64 | 1.03 | .92 | 1.15 |
| Last year use | -.008 | .85 | .99 | .91 | .108 |
| Anxiety disorder | .234 | .01 | 1.26 | 1.05 | 1.51 |
| Depressive disorder | .110 | .18 | 1.12 | .95 | 1.31 |
| Substance use disorder | .016 | .88 | 1.02 | .82 | 1.25 |
| Alcohol use disorder | .090 | .39 | 1.09 | .89 | 1.34 |
| Physical health conditions | .101 | .04 | 1.10 | 1.01 | 1.22 |
| Acute spiritual experience | .016 | < .001 | 1.02 | 1.01 | 1.02 |
| Context | |||||
| Religious context | – | – | 1 | ||
| Traditional Shaman context | .230 | .02 | 1.26 | 1.03 | 1.53 |
| Non-traditional context | .453 | < .001 | 1.57 | 1.31 | 1.89 |
| Non-supervised context | .538 | < .001 | 1.71 | 1.28 | 2.29 |
| Adverse emotional-congnitive effects | |||||
| Age of initial use | .012 | .09 | 1.01 | 1.00 | 1.03 |
| Doses/year | .014 | .83 | 1.01 | .89 | 1.15 |
| Lifetime use | .008 | .89 | 1.01 | .90 | 1.13 |
| Last year use | -.052 | .22 | .95 | .87 | 1.03 |
| Anxiety disorder | .357 | < .001 | 1.43 | 1.20 | 1.70 |
| Depressive disorder | .146 | .07 | 1.16 | .99 | 1.35 |
| Substance use disorder | -.010 | .93 | .99 | .80 | 1.22 |
| Alcohol use disorder | -.014 | .89 | .99 | .80 | 1.21 |
| Physical health conditions | .062 | .20 | 1.06 | .97 | 1.17 |
| Acute spiritual experience | .011 | < .001 | 1.01 | 1.01 | 1.01 |
| Context | |||||
| Religious context | – | – | 1 | ||
| Traditional Shaman context | .193 | .05 | 1.21 | 1.00 | 1.47 |
| Non-traditional context | .454 | < .001 | 1.57 | 1.31 | 1.89 |
| Non-supervised context | .447 | .002 | 1.56 | 1.18 | 2.06 |
| Adverse psychotomimetic effects | |||||
| Age of initial use | .021 | .002 | 1.02 | 1.01 | 1.03 |
| Doses/year | -.088 | .19 | .92 | .80 | 1.04 |
| Lifetime use | .173 | .003 | 1.19 | 1.06 | 1.33 |
| Last year use | .025 | .54 | 1.03 | .94 | 1.11 |
| Anxiety disorder | .134 | .13 | 1.14 | .96 | 1.36 |
| Depressive disorder | .141 | .08 | 1.15 | .98 | 1.35 |
| Substance use disorder | .161 | .12 | 1.17 | .96 | 1.44 |
| Alcohol use disorder | .046 | .65 | 1.05 | .85 | 1.28 |
| Physical health conditions | .174 | < .001 | 1.19 | 1.08 | 1.31 |
| Acute spiritual experience | .023 | < .001 | 1.02 | 1.02 | 1.03 |
| Context | |||||
| Religious context | – | – | 1 | ||
| Traditional Shaman context | .248 | .01 | 1.28 | 1.05 | 1.56 |
| Non-traditional context | .307 | .001 | 1.36 | 1.13 | 1.63 |
| Non-supervised context | .419 | .003 | 1.52 | 1.15 | 2.01 |
1 Significant controlled variables: Adverse mental health effects: female: β = .16; p = .006; OR = 1.17 (1.05–1.32); age at survey day: β = -.02; p = .007; OR = .98 (.97-.99); married: β = - .38; p < .001; OR = .68 (.58-.79); Adverse emotional-cognitive effects: female β = .16; p = .006; OR = 1.18 (1.05–1.32); age at survey day: β = -.02; p = .002; OR = .98 (.96-.99); married β = - .44; p < .001; OR = .64 (.55-.74); Adverse psychotomimetic effects: female β = .18; p = .002; OR = 1.19 (1.07–1.34); age at survey day: β = -.02; p = .001; OR = .98 (.96-.99); married β = - .27; p = .001; OR = .76 (.65-.89).