Table 4. Summary of infant outcomes and certainty of evidence.
Outcomes | Clinical evidence | Favours planned VD | Favours planned CS | Certainty of evidence* |
---|---|---|---|---|
Brachial plexus injury | The incidence of brachial plexus injury was lower, with borderline statistical significance, in prelabour CS compared to VD [22, 27] | Low | ||
Neonatal cardio-respiratory disorders | Elective CS was associated with a 2-3-fold increase in the risk for neonatal respiratory problems, including transient tachypnea of the newborn, respiratory distress syndrome, and persistent pulmonary hypertension [20, 22, 27, 28] | Low | ||
Childhood obesity | There is evidence of a possible association between all types of CS and increased risks for excess adiposity in childhood and adolescence [24, 29] | Moderate | ||
Childhood allergies | Significant increased risks for allergic rhinitis, food allergy, and asthma in children delivered through all types of CS compared with children delivered vaginally [24, 30–32] | Moderate |
VD = vaginal delivery; CS = caesarean section
*Certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) scale