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. 2023 Jan 24;3(1):e0000477. doi: 10.1371/journal.pgph.0000477

Table 2. History of antibiotics used by the patients, presence of toxigenic C. difficile, and disease severity among pediatric patients with diarrhea.

Measure N (%) CDI
Positive Negative
n (%) n (%)
Parent’s Knowledge of Antibiotics
No 49 (66.2) 16 (21.6) 33 (44.6)
Yes 25 (33.8) 14 (18.9) 11 (14.9)
Test Statistics: χ2 value, P-value 3.743, 0.0530*
Use Antibiotics in the last 14 days
No 44 (71.0) 14 (22.6) 30 (48.4)
Yes 18 (29.0) 11 (17.7) 7 (11.3)
Test Statistics: χ2 value, P-value 4.555, 0.0328*
Type of Antibiotic Used in the last 14 days
Metronidazole/Flaggy 10 (13.2) 7 (9.2) 3 (4.0)
Other types of Antibiotics 7 (9.2) 4 (5.3) 3 (4.0)
Unknown 59 (77.6) 20 (26.3) 39 (51.3)
Test Statistics: χ2 value, P-value 5.468, 0.0650
Used Antibiotics in the Last 90 days (3 Months)
No 52 (70.3) 20 (27.0) 32 (43.2)
Yes 22 (29.7) 11 (14.9) 11 (14.9)
Test Statistics: χ2 value, P-value 0.846, 0.3578
Last occurrence of diarrhea prior to clinic visit
Less than 14 days 24 (55.8) 15 (34.9) 9 (20.9)
Last 1 or more months 19 (44.2) 7 (16.3) 12 (27.9)
Test Statistics: χ2 value, P-value 2.794; 0.0946
Ailment Experienced prior to Clinic visit
Vomiting 25 (32.9) 11 (14.5) 14 (18.4)
Non-vomiting 30 (39.5) 10 (13.2) 20 (26.3)
Unknown 21 (27.6) 10 (13.2) 11 (14.5)
Test Statistics: χ2 value, P-value 1.203; 0.5480
Severity of Diarrhea
Mild 14 (19.7) 7 (9.9) 7 (9.9)
Moderate 47 (66.2) 18 (25.4) 29 (40.9)
Severe 10 (14.1) 3 (4.2) 7 (9.9)
Test Statistics: χ2 value, P-value 1.052; 0.5908
Hospitalization due to Diarrhea
No 49 (68.1) 20 (27.8) 29 (40.3)
Yes 23 (31.9) 9 (12.5) 14 (19.4)
Test Statistics: χ2 value, P-value 0.018; 0.8918

Note: Within measure percentages may not add up to 100 exactly due to rounding; within characteristic, “n” may not add up to the total number of records due to missing response.

Significance Level

* = p<0.05; ns = not significant (p>0.05).