Table 1.
Biologic and Clinic features of the patients and healthy subjects enrolled in the study
| Characteristics | Small-RNA Seq cohort | Cohort for comparison gliomas vs controls | ||
|---|---|---|---|---|
| IDH-wt (n = 27) | IDH-mut (n = 10) | Gliomas (n = 15) | Healthy subjects (n = 15) | |
| Age | ||||
| Median | 59 | 47 | 50 | 51 |
| Range | 24–77 | 29–77 | 23–70 | 23–70 |
| Gender | ||||
| Males | 20 | 7 | 9 | 9 |
| Females | 7 | 3 | 6 | 6 |
| Histology | ||||
| Glioblastoma, IDH-wt | 25 | – | 9 | – |
| Astrocytoma, IDH-mut | – | 3 | 1 | – |
| Oligodendroglioma | 0 | 6 | 2 | – |
| Glial neoplasia, unspecified | 2 | 1 | 3 | – |
| IDH mutation status | ||||
| wild type | 27 | 0 | 8 | – |
| IDH1 mutant | 0 | 10 | 6 | – |
| IDH2 mutant | 0 | 0 | 1 | – |
| 1p19q status | ||||
| Non codeleted | 27 | 3 | 13 | – |
| Co-deleted | 0 | 4 | 2 | – |
| Unknown | 0 | 3 | 0 | – |
| MGMT promoter status | ||||
| Methylated | 15 | 5 | 6 | – |
| Unmethylated | 12 | 3 | 7 | – |
| Unknown | 0 | 2 | 2 | – |