Table 1.
Predictive SNPs in the Desikan Nordic model and their effects on the log proportional hazard of developing Alzheimer’s disease. The given call rate and MAF are for the DemGene model development population.
| rsID | Chromosome | Position (bp) | Reference Allele | Alternative Allele | Call rate | MAF | SNP Effect | 95%CI-L | 95%CI-U |
|---|---|---|---|---|---|---|---|---|---|
| rs7581787 | 2 | 234,077,240 | A | C | 0.998 | 0.481 | 0.16 | 0.13 | 0.18 |
| rs35112405 | 8 | 27,511,807 | A | T | 0.999 | 0.05 | −0.48 | −0.53 | −0.42 |
| rs480781 | 11 | 85,795,950 | A | G | 0.994 | 0.29 | −0.14 | −0.15 | −0.1 |
| rs1549299 | 16 | 31,154,146 | G | A | 0.993 | 0.287 | −0.09 | −0.16 | −0.05 |
| rs57355367 | 19 | 45,698,085 | A | G | 0.964 | 0.122 | 0.19 | 0.16 | 0.21 |