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. 2022 Dec 21;2(12):e0000914. doi: 10.1371/journal.pgph.0000914

Table 4. Results of sub-group analysis for prevalence of CHIKV infection among children based on continent, study setting, diagnostic technique, study design and season.

Subgroup analyses
Number of studies Proportion in % (95% CI) I2, %
Continent
Africa 17 8.86 [4.42; 16.98] 97.2
Asia 20 8.78 [3.87; 18.70] 97.8
North America 6 22.20 [4.22; 64.89] 99.3
South America 10 22.83 [7.50; 51.88] 92.5
Study setting    
Hospital/health centre 37 13.02 [7.36; 21.99] 98.1
Community 11 10.11 [4.38; 21.64] 98.1
Unspecified 5 7.52 [0.68; 49.25] 91.3
Diagnostic technique    
Detection of anti-CHIKV IgM 19 11.09 [6.11; 19.31] 97.3
Detection of CHIKV RNA 22 14.64 [6.64; 29.27] 97.7
Detection of anti-CHIKV IgM and CHIKV RNA 12 8.56 [2.42; 26.12] 98.4
Study design    
Longitudinal 22 11.84 [5.14; 24.96] 98.5
Cross-sectional 21 8.75 [4.65;15.88] 97.4
Unspecified 10 21.08 [8.46; 43.55] 95.5
Season    
Epidemic 27 18.46 [10.52; 30.37] 98.4
Non-epidemic 6 3.86 [1.91; 7.62] 89.7
Epidemic/Non-epidemic 1 8.36 [5.97; 11.58] NA
Unspecified 19 8.59 [3.36; 20.23] 96.7