Table 4.

Acute and late severe and life-threatening toxicities (grade 3 and 4 according to CTCAE v5.0) of (chemo)radiotherapy in elderly patients with SCC of the esophagus.

Variable	Value
Acute toxicities – no. (%)	51 (31.7)
- Hematological side effects – no. (%)	27 (16.8)
- Dysphagia – no. (%)	27 (16.8)
- Esophageal stenosis – no. (%)	9 (5.6)
- Mucositis/odynophagia – no. (%)	10 (6.2)
- Acute renal failure – no. (%)	2 (1.2)
- Tumor bleeding – no. (%)	4 (2.5)
- Fistula – no. (%)	1 (0.6)
- Pneumonia – no. (%)	2 (1.2)
- Perforation and mediastinitis – no. (%)	1 (0.6)
- Pulmonary artery embolism – no. (%)	2 (1.2)
- Damage to the vestibular organ – no. (%)	1 (0.6)
- Radiation dermatitis – no. (%)	1 (0.6)
Late toxicities – no. (%)	22 (13.7)
- Dysphagia – no. (%)	19 (11.8)
- Esophageal stenosis – no. (%)	18 (11.2)
- Ulcera with tumor bleeding and lethal outcome – no. (%)	2 (1.2)
- Diarrhea – no. (%)	1 (0.6)