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. 2023 Mar 3;10:1100486. doi: 10.3389/fmolb.2023.1100486

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Copyright © 2023 López-Hernández, Oropeza-Valdez, García Lopez, Borrego, Murgu, Valdez, López and Monárrez-Espino.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Variable importance in Projection (VIP) plot representing the rank of 15 features identified by PLS-DA according to VIP score on x-axis. The most discriminating metabolites are shown in descending score order. The color boxes indicate whether metabolite concentration was increased (red) or decreased (blue). Figures were produced in MetaboAnalyst software v 5.0 (https://www.metaboanalyst.ca/). * Represents features with confidence level 2 and ♦ represents features with level 3.