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. Author manuscript; available in PMC: 2023 Mar 17.
Published in final edited form as: Cancer Treat Res Commun. 2020 Dec 13;26:100286. doi: 10.1016/j.ctarc.2020.100286

Figure 4 |. ATII differentiation and NKX2-1 addition share transcriptional changes associated with STK11 signaling.

Figure 4 |

(a) Volcano plot of gene expression changes as a result of type II pneumocyte differentiation. (b) Volcano plot of gene expression changes as a result of NKX2-1 addition to A549 cells. (c) Expression of genes pertaining to ATII differentiation in the top and bottom 10% of patients based on NKX2-1 expression in both STK11 WT and loss patients (d) Swarm plot of PC-1 (left) and PC-2 (right) in ATII differentiation study. (e) Swarm plot of the neuroendocrine signature (left) and the differentiation signature (right) in NKX2-1 addition study.