TABLE 1.
Item | Responses | Proportion agreement (%) |
---|---|---|
In a clinical practice setting, IBD-associated EN should be recognised by | Dermatologist | 100 |
An IBD specialist | 100 | |
IBD-associated EN should be clinically diagnosed by | Dermatologist | 100 |
An IBD specialist | 94 | |
IBD-associated EN should be defined in the clinical practice setting based on | Characteristic appearance of erythematous nodule(s) plus patient report of tenderness | 100 |
A lesion with features of septal panniculitis on biopsy if there is diagnostic uncertainty on physical exam | 100 | |
The average patient with IBD-associated EN can be monitored via | Visits to IBD specialist | 88 |
Visits to Dermatologist | 88 | |
The average patient with IBD-associated EN should be seen | At the time of scheduled assessment of IBD with mild disease and every 1–3 months for moderate to severe disease requiring active intervention | 88 |
Appropriate ways to assess for improvement or worsening in IBD-associated EN include | Patient report of a change in size and/or number of nodules | 88 |
Patient global assessment | 82 | |
Physician assessment demonstrating change in size | 75–83a | |
Physician assessment of change in the number of nodules | 76–82a | |
Physician global assessmentb | 76–94a | |
Resolution of IBD-associated EN is defined as | Patient report of resolution | 88 |
Physician assessment demonstrating no nodule(s) | 88 | |
Recurrence of IBD-associated EN is defined as | Nodule(s) that develop anywhere | 100 |
Timeline of recurrence of IBD-associated EN is defined as | Patient report of the nodule(s) returning any time after resolution | 82 |
Physician assessment of nodule(s) returning any time after resolution | 88 | |
Patients with IBD-associated EN should be monitored for recurrence | As part of standard of care visits with their IBD specialist | 94 |
As part of standard of care visits with dermatology | 88 |
Abbreviations: EN, erythema nodosum; IBD, inflammatory bowel disease.
Range in percentage is due to the inclusion of percentage agreement for improvement and for worsening (see Table S2 for a breakdown of percentages by individual items).
Physician global assessment was defined by our panel with 100% consensus as the overall status of EIM based on patient symptoms, physical exam, and any relevant testing (imaging, laboratory data).