Table 4. Clinical trial methods and terminologies.

This table has been created by the authors.

Type of clinical trial	Definition
Randomized trial	Study participants are randomly assigned to a group
Open-label	Both study subjects and the researchers are aware of the drug being tested
Blinded (single-blind)	In single-blind studies, the subject has no idea about the group (test/control) in which they are placed
Double-blind (double-blind)	In the double-blind study, the subjects as well as the investigator have no idea about the test/control group
Placebo	A substance that appears like a drug but has no active moiety
Add-on	An additional drug apart from the clinical trial drug given to a group of study participants
Single center	A study being carried out at a particular place/location/center
Multi-center	A study is being carried out at multiple places/locations/centers