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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Trends Mol Med. 2023 Feb 22;29(4):315–328. doi: 10.1016/j.molmed.2023.01.007

Figure 3. Modulation of bilirubin level.

Figure 3.

Several approaches can be used to mildly elevate the plasma bilirubin level above the optimal threshold. These include (i) Lifestyle approach (proper body composition, modest calorie restriction with a healthy diet rich in carbohydrates, fruit and vegetables, and sufficient aerobic activities); (ii) Nutraceutical approach, and finally; (iii) Pharmacological approach including nutraceuticals and drugs modulating HMOX/UGT1A1 activities as well as hepatic bilirubin transporting functions.

This figure was created by Matthew Hazzard at the University of Kentucky College of Medicine.