Table 3:
Totals (% of total) | Local failure | Regional failure | Distant failure | Deaths | Deaths related to progression or recurrence | ||
---|---|---|---|---|---|---|---|
| |||||||
Swallowing | High | 52 | 4 (7.7%) | 4 (7.7%) | 4 (7.7%) | 6 (11.5%) | 4 (7.7%) |
Low | 418 | 2 (0.5%) | 17 (4.1%) | 19 (4.5%) | 6 (1.4%) | 3 (0.7%) | |
| |||||||
p-value | 0.002 | 0.273 | 0.305 | 0.001 | 0.004 | ||
| |||||||
Choke | High | 26 | 2 (7.7%) | 2 (7.7%) | 4 (15.4%) | 4 (15.4%) | 3 (11.5%) |
Low | 444 | 4 (0.9%) | 19 (4.3%) | 19 (4.3%) | 8 (1.8%) | 4 (0.9%) | |
| |||||||
p-value | 0.039 | 0.326 | 0.027 | 0.003 | 0.005 | ||
| |||||||
Shortness of breath | High | 44 | 2 (4.5%) | 3 (6.8%) | 6 (13.6%) | 4 (9.1%) | 3 (6.8%) |
Low | 426 | 4 (0.9%) | 18 (4.2%) | 17 (4.0%) | 8 (1.9%) | 4 (0.9%) | |
| |||||||
p-value | 0.101 | 0.434 | 0.014 | 0.019 | 0.021 | ||
| |||||||
Composite variable | High | 8 | 1 (12.5%) | 1 (12.5%) | 2 (25%) | 3 (37.5%) | 2 (25%) |
Low | 462 | 5 (1.1%) | 20 (4.3%) | 21 (4.5%) | 9 (1.9%) | 5 (1.1%) | |
| |||||||
p-value | 0.098 | 0.308 | 0.054 | 0.001 | 0.005 |
Thresholds for “high” versus “low” MDASI score categories stated: “high” for swallow is a score≥6; for choke, a score≥6; and for shortness of breath, a score≥2. For the composite variable “high” is denoted as having “high” scores for all three symptoms, versus “low” denoting “high” scores for two or fewer symptoms. P-values obtained using Fisher’s exact test.