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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Radiother Oncol. 2023 Jan 11;180:109465. doi: 10.1016/j.radonc.2023.109465

Table 3:

Outcomes for patients with high versus low scores for MDASI for swallow, choke, and shortness of breath.

Totals (% of total) Local failure Regional failure Distant failure Deaths Deaths related to progression or recurrence

Swallowing High 52 4 (7.7%) 4 (7.7%) 4 (7.7%) 6 (11.5%) 4 (7.7%)
Low 418 2 (0.5%) 17 (4.1%) 19 (4.5%) 6 (1.4%) 3 (0.7%)

p-value 0.002 0.273 0.305 0.001 0.004

Choke High 26 2 (7.7%) 2 (7.7%) 4 (15.4%) 4 (15.4%) 3 (11.5%)
Low 444 4 (0.9%) 19 (4.3%) 19 (4.3%) 8 (1.8%) 4 (0.9%)

p-value 0.039 0.326 0.027 0.003 0.005

Shortness of breath High 44 2 (4.5%) 3 (6.8%) 6 (13.6%) 4 (9.1%) 3 (6.8%)
Low 426 4 (0.9%) 18 (4.2%) 17 (4.0%) 8 (1.9%) 4 (0.9%)

p-value 0.101 0.434 0.014 0.019 0.021

Composite variable High 8 1 (12.5%) 1 (12.5%) 2 (25%) 3 (37.5%) 2 (25%)
Low 462 5 (1.1%) 20 (4.3%) 21 (4.5%) 9 (1.9%) 5 (1.1%)

p-value 0.098 0.308 0.054 0.001 0.005

Thresholds for “high” versus “low” MDASI score categories stated: “high” for swallow is a score≥6; for choke, a score≥6; and for shortness of breath, a score≥2. For the composite variable “high” is denoted as having “high” scores for all three symptoms, versus “low” denoting “high” scores for two or fewer symptoms. P-values obtained using Fisher’s exact test.