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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Curr Opin Struct Biol. 2023 Feb 28;79:102550. doi: 10.1016/j.sbi.2023.102550

Figure 4.

Figure 4.

Qualitative correlation between binding affinity (Kd) and intermolecular hydrogen bonding and π-stacking interactions for fragment-like ligands that engage RNA. Note: plotting Kd values on a logarithmic scale yields a relationship proportional to ΔG. Complexes are the same as shown in Fig. 3.