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. 2022 Jul 7;73(2):186–194. doi: 10.1016/j.identj.2022.05.004

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 2 — Differential expression analysis of GSE10334 and GSE54710. A, Volcano plot of mRNA expression level in GSE10334, mRNAs with adjusted P value <.01 and log2(FC) >1.0 are shown by the red dot, whereas mRNAs with adjusted P value <.01 and log2(FC) <−1 are shown by the blue dot. B, Volcano plot of miRNAs expression level in GSE54710, miRNAs, with P value <.05 and log2(FC) >0.5 are shown by the red dot, whereas miRNAs with P value <.05 and log2(FC) <−0.5, are shown by the blue dot. C, The heatmap shows the expression of the top 20 up-regulated mRNAs and down-regulated mRNAs. D, The heatmap shows the expression of the top 20 up-regulated miRNAs and down-regulated miRNAs. E, The Venn diagram shows the overlapping parts of the differentially expressed genes (DEGs) and ferroptosis-related genes (FRGs), identifying 7 differentially expressed ferroptosis-related genes (DE-FRGs). F, Spearman correlation analysis of the 7 DE-FRGs.