Fig. 6.

Effects of AA on learning and memory in Morris water maze test: The dose-dependent impact of AA on learning and memory was evaluated by testing the rats (n = 8) to locate the disguised platform for 3 test days and the duration to reach the platform were noted as (a) escape latencies. The long-term memory was examined by testing the rats on probe day for their (b) entries in the platform zone and (c) duration spent in the platform zone. During three test days and one probe day, the animals were treated with AA 60 min before their testing in MWM test followed by administration of scopolamine 30 min before experiment. The effects of AA on learning and memory of animals were determined by monitoring their All data were expressed as mean ± SD and escape latencies were evaluated by two-way ANOVA with Tukey's test while entries and duration in target quadrant were evaluated by one-way ANOVA followed by Dunnet’s test. ^#P < 0.05, *P < 0.05, ^bP < 0.05 and ^cP < 0.05 were considered as significant for control, piracetam, AA 100 and AA 200 compared to scopolamine-treated amnesic rats, respectively.