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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2022 Sep 18;166(1):e5–e14. doi: 10.1016/j.jtcvs.2022.09.019

Figure 2: Angiostatin and endostatin expression are decreased with extracellular vesicle therapy in chronically ischemic myocardium.

Figure 2:

The high-fat diet with EV injection (HVM, n=8) group had significant decreases in expression of anti-angiogenic markers angiostatin and endostatin compared to the control group (n=6). Upper and lower borders of box represent upper and lower quartiles, middle horizontal line represents median, upper and lower whiskers represent maximum and minimum values of non-outliers. ***p<0.001, *p<0.05 as determined by Wilcoxon rank-sum test.