Table 2.
Comparison between male and female infants (who survived to 7 days), who did not receive PNS
| Male n = 4359 | Female n = 3952 | P value | |
|---|---|---|---|
| Gestational age | 26.57 (25.42–27.28) | 26.42 (25.28–27.28) | < 0.001 |
| Birth weight (grams) | 900 (760–1035) | 828.5 (700–960) | < 0.001 |
| Birth weight (z score) | −0.332 (−0.81–0.11) | −0.318 (−0.80–0.118) | 0.403 |
| Antenatal steroids | 3946 (90.5%) | 3531 (89.3%) | 0.199 |
| Surfactant given | 3820 (87.6%) | 3441 (87.1%) | 0.933 |
| Died before NNU discharge | 465 (10.7%) | 343 (8.7%) | 0.003 |
| Discharge weight (grams) | 2576 (2140–3100) | 2425 (2050–2888.5) | < 0.001 |
| Discharge weight (z score) | −1.45 (−2.14– −0.782) | −1.46 (−2.21– −0.819) | 0.035 |
| PMA discharge | 38.67 (36.67–40.83) | 38.46 (36.65–40.63) | 0.204 |
| Mechanical respiration (days) | 9.0 (3–20) | 7.0 (2–17) | < 0.001 |
| Respiratory support at 28 days | 3726 (85.5%) | 3387 (85.7%) | < 0.001 |
| Surgery for NEC | 650 (14.9%) | 504 (12.8%) | 0.004 |
| TPN (days) | 15.0 (10–24) | 14.0 (10–23) | 0.215 |
| IVH grade 3 or greater | 636 (14.6%) | 442 (11.2%) | < 0.001 |
| ROP treatment | 342 (7.8%) | 318 (8%) | 0.784 |
| Cystic PVL | 164 (3.8%) | 129 (3.3%) | 0.341 |
| Including only infants surviving to 36 weeks, n = 9614. Not receiving PNS n = 7545 | |||
| Male n = 3919 | Female n = 3628 | P value | |
| BPD | 2577 (65.8%) | 2146 (59.2%) | < 0.001 |
| Home on O2 | 1347 | 1095 | < 0.001 |
Data are demonstrated as n (%) or median (IQR)
PMA post menstrual age, NEC necrotizing enterocolitis, TPN total parenteral nutrition, IVH intraventricular hemorrhage, ROP retinopathy or prematurity, PVL periventricular leukomalacia, BPD bronchopulmonary dysplasia