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. 2023 Mar 17;6:278. doi: 10.1038/s42003-023-04663-y

Fig. 3. Chronic treatment with empagliflozin reverses mitochondrial ATP loss in the heart of T2D model mice.

Fig. 3

a Schematic illustration of the treatment regimen (EMPA empagliflozin). b–d Representative fluorescence images of a live heart from each condition (EMPA empagliflozin). Warmer colors indicate higher ATP concentrations. Scale bar: 2 mm. e FRET/GFP ratios indicating the mitochondrial ATP level in the heart under each condition (+/+ (control): n = 11, db/db (control): n = 10, db/db (EMPA): n = 17). *p = 0.000).