Table 6.
Multidrug-resistance of hvKp isolates producing ESBLs.
| Source | Combination of drugs (No. of antimicrobial agents classes) | Virulence genes |
|---|---|---|
| Blood | CTX,CXM,SXT,CIP (3) | rmpA,entB,irp-1,mrkD |
| Urine | AMC,CTX,CXM,GM,SXT,CIP (4) | rmpA,entB,irp-1,clbA,clbB |
| Urine | AMC,TZP,CTX,CXM,SXT,CIP (3) | rmpA,entB,irp-1,mrkD,wcaG |
| Urine | AMC,TZP,CTX,CXM,SXT,CIP (3) | iroD,entB, irp-1,mrkD |
| Urine | TZP,CTX,CXM,SXT,CIP (3) | iroD,entB, irp-1,mrkD, fimH |
| Urine | AMC,TZP,CTX,CXM,SXT,CIP (3) | iroD,iroN,entB,irp-1,mrkD, fimH,wcaG |
| Respiratory tract | AMC,TZP,CTX,CXM,SXT,CIP (3) | iroD,iroN,entB, irp-1,mrkD, fimH |
| Respiratory tract | AMC,CTX,CXM,SXT,CIP (3) | iroD,iroN,entB,irp-1,mrkD, fimH,wcaG |
| Blood | AMC,CTX,CXM,GM,AMK,SXT,CIP (4) | iroN,entB, irp-1,mrkD,kfu |
| Blood | AMC,CTX,CXM,TZP,GM,SXT,CIP (4) | iroN,entB,mrkD |
AMC—amoxicillin plus clavulanic acid, TZP—piperacillin plus tazobactam CTX—cefotaxime, CXM—cefuroxime, AMK—amikacin, GM—gentamicin, CIP—ciprofloxacin, SXT—trimethoprim plus sulfamethoxazole.