Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 17;6:279. doi: 10.1038/s42003-023-04637-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Schematic diagram of dynamic segregation and integration analysis. The brain functional connectivity (FC) network temporally switches between segregated (low FC) and integrated (high FC) state. Using the NSP method, this dynamic transition can be studied separately in two dimensions: dynamic segregation and integration. The white lines indicate the mean values, and the ranges of the y-axis are indicated by the color bars. b Comparisons of integration strength H_In and c segregation strength H_Se between the healthy control (HC, n = 50) and schizophrenia (SCH, n = 50) groups. Each point indicates the value of an individual, and the boxplot of each group was also provided. ** indicates a significant group difference with p < 0.01, *** p < 0.001. d Relative changes in integration strength H_In and segregation strength H_Se from HC to SCH in seven functional systems. All systems had significant alterations (p < 0.05, FDR corrected). e Comparisons of integration variability F_In, f segregation variability F_Se between HC and SCH groups. g Relative changes in the integration variability F_In and segregation variability F_Se from HC to SCH in seven functional systems. All systems had significant alterations (p < 0.05, FDR corrected). VIS: visual, MOT: motor, DOR: dorsal attention, SAL: salient attention, LIM: limbic, CON: control, DMN: default-mode network (see similar results for the brain parcellation of 500 regions in Supplementary Fig. 3).