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. 2023 Mar 3;14:1142805. doi: 10.3389/fendo.2023.1142805

Table 2.

The role of single herbs against renal injuries via regulating autophagy in DKD.

Signaling Pathways Single herbs In Vivo/In Vitro Model References
LC3-II-RIP-p38MAPK Cassia auriculata leaf extract In Vivo/In Vitro STZ-induced rats, rat glomerular endothelial cells induced by HG (22)
PI3K/Akt/mTOR Radix astragali In Vivo/In Vitro STZ-induced mice, mouse podocytes (23)