Table 2.
Neuroanatomical associations of reward behaviour in the combined patient cohort
| Region | Side | Cluster (voxels) | Peak (mm) | T score | P FWE | ||
|---|---|---|---|---|---|---|---|
| X | Y | Z | |||||
| Anterior cingulate gyrus | L | 407 | −6 | 26 | 22 | 4.34 | 0.018 |
| Temporal pole | R | 1198 | 30 | 14 | −30 | 4.11 | 0.020 |
| 26 | 4 | −45 | 4.09 | 0.021 | |||
| 32 | −4 | −40 | 4.00 | 0.029 | |||
| L | 146 | −27 | 4 | −51 | 4.04 | 0.025 | |
| −21 | 12 | −44 | 3.94 | 0.036 | |||
| Middle frontal gyrus | R | 94 | 38 | 6 | 63 | 4.07 | 0.023 |
| Fusiform gyrus | R | 52 | 44 | −22 | −24 | 3.89 | 0.042 |
The table shows grey matter regions from the VBM analysis significantly positively associated with the leading reward factor (factor 1) over the combined patient cohort. Local maxima shown attained significance threshold (P < 0.05) after family-wise error correction for multiple voxel-wise comparisons over the whole brain. Coordinates are in standard Montreal Neurological Institute space. All clusters with extent larger than 50 voxels are presented.