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. 2023 Mar 8;14:285–292. doi: 10.1016/j.ibneur.2023.03.004

Table 2.

Diagnostic accuracy of proteins in AD (Alzheimer’s disease) group.

Cutoff point Sensitivity (%) Specificity (%) PPV (%) NPV (%) AUC P-value
60.3 62.5 91 88.2 68.9 0.81 < .001
P-tau 5.1 91.7 63.6 73.3 87.5 0.78 .001
Total α-syn 9.4 66.7 68.2 69.5 65.2 0.71 .015

PPV & NPV: Positive predictive value and negative predictive value. AUC: Area under the curve.