Figure 9.

Cellular ablation of the AV node of iAVB (Tg^{Cx30.2-MerCreMer/+}; Rosa26^DTA/LacZ) mouse heart after Tamoxifen induction

(A and B) Masson’s trichrome staining of the AV node of iAVB mouse compared to control, scale bar: 100 μm.

(C) Quantification of the AVN fibrosis of iAVB mouse compared to control, ∗p-value <0.05. Error bars represent SEM.

(D and E) HCN4 immunofluorescence staining of the AV node of iAVB mouse compared to control, scale bar: 100 μm.

(F) Quantification of HCN4 positive cell dropout in the AVN of iAVB mouse compared to control, ∗∗p-value <0.01. Error bars represent SEM.