Table 5.
Main Clinical Symptoms, Physical Activity, and Quality of Life Outcomes
| |
CART+PR |
|
PR alone |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Na | Mean (SD)-pre | Mean (SD)-post | Within-group difference (CI) | p | Cohen's d effect size | N | Mean (SD)-pre | Mean (SD)-post | Within-group difference (CI) | |
| DMQ Dyspnea Anxiety | 13 | 56.02 ± 7.22 | 58.45 ± 6.27 | 2.43 (0.09 to 4.77) | 0.04 | 0.35 | 3 | 56.54 ± 3.41 | 53.38 ± 3.59 | −3.16 |
| SGRQ Symptoms | 13 | 53.69 ± 18.1 | 37.93 ± 24.61 | −15.76 (−28.06 to −3.47) | 0.02 | 0.71 | 3 | 46.85 ± 22.27 | 45.37 ± 6.62 | −1.48 |
| SGRQ Activity | 13 | 68.16 ± 17.74 | 60.56 ± 18.39 | −7.6 (−16.85 to 1.65) | 0.1 | 0.42 | 3 | 82.02 ± 10.4 | 71.23 ± 8.74 | −10.79 |
| SGRQ Impacts | 12 | 41.93 ± 22.11 | 29.79 ± 17.85 | −12.14 (−19.88 to −4.4) | 0.01 | 0.57 | 3 | 44.05 ± 14.03 | 32.77 ± 1.74 | −11.28 |
| SGRQ Total | 12 | 52.47 ± 18.08 | 40.72 ± 16.48 | −11.76 (−19.68 to −3.83) | 0.01 | 0.68 | 3 | 56.65 ± 11.79 | 46.69 ± 0.85 | −9.96 |
| CRQ Mastery | 13 | 5.15 ± 1.53 | 5.58 ± 1.08 | 0.42 (−0.34 to 1.18) | 0.25 | 0.31 | 3 | 5.33 ± 1.04 | 5.33 ± 1.15 | 0 |
| PROMIS Anxiety | 13 | 53.18 ± 9.89 | 51.26 ± 9.22 | −1.92 (−6.24 to 2.41) | 0.35 | 0.2 | 3 | 63.97 ± 13.38 | 63.07 ± 14.16 | −0.9 |
| PROMIS Depression | 13 | 51.54 ± 10.11 | 48.77 ± 9.1 | −2.77 (−6.39 to 0.85) | 0.12 | 0.28 | 3 | 62.03 ± 8.71 | 58.6 ± 14.2 | −3.43 |
| PROMIS Fatigue | 13 | 53.64 ± 9.14 | 49.45 ± 8.41 | −4.18 (−8.16 to −0.21) | 0.04 | 0.47 | 3 | 54.3 ± 5.77 | 59.5 ± 10.05 | 5.2 |
| PROMIS Sleep Disturbance | 13 | 53.17 ± 7.22 | 51 ± 6.24 | −2.17 (−4 to −0.34) | 0.02 | 0.31 | 3 | 53.03 ± 7.7 | 54.07 ± 12.4 | 1.03 |
| PROMIS Social Roles | 13 | 49.6 ± 10.37 | 50.95 ± 9.52 | 1.35 (−2.28 to 4.97) | 0.43 | 0.13 | 3 | 40.63 ± 14.65 | 45.23 ± 5.3 | 4.6 |
| PROMIS Physical Function | 13 | 38.53 ± 5.22 | 41.28 ± 5.11 | 2.75 (0.1 to 5.39) | 0.04 | 0.53 | 3 | 33.1 ± 2.63 | 36.13 ± 3.06 | 3.03 |
| SEBQ Total (lower is better) | 13 | 12.08 ± 6.78 | 8.92 ± 5.56 | −3.15 (−6.42 to 0.11) | 0.06 | 0.5 | 3 | 12.67 ± 2.31 | 11.67 ± 1.15 | −1 |
| MVPA | 13 | 63.85 ± 81.6 | 150.77 ± 130.8 | 86.92 (17.96 to 155.88) | 0.02 | 0.76 | 3 | 26.67 ± 30.55 | 140 ± 192.87 | 113.33 |
| GAD-7 | 13 | 4.15 ± 4.14 | 3.62 ± 2.87 | −0.54 (−1.97 to 0.89) | 0.43 | 0.13 | 3 | 8.67 ± 6.03 | 8.67 ± 7.23 | 0 (−6.57 to 6.57) |
The paired two-sample t test was used.
a
N is the number of subjects who have both pre- and post-data.
CART, capnography-assisted respiratory therapy; CI, confidence interval; CRQ, Chronic Respiratory Disease Questionnaire. DMQ, Dyspnea Management Questionnaire; GAD-7, Generalized Anxiety Disorder Scale; MVPA, moderate to vigorous physical activity; PR, pulmonary rehabilitation; PROMIS, Patient-Reported Outcomes Measurement Information System; SD, standard deviation; SEBQ, Self-Evaluation of Breathing Questionnaire; SGRQ, St. George's Respiratory Questionnaire.