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. 1999 Jul;12(3):367–382. doi: 10.1128/cmr.12.3.367

FIG. 5.

FIG. 5

(A) SalI restriction map of the HHV-6 strain U1102 genome showing the locations of transforming regions (86, 140, 178) and genes that transactivate the HIV-1 LTR promoter (57, 87, 117, 181, 185, 196). Below each transactivating gene are indicated (i) the fragment in which the gene was originally identified, (ii) the common gene name, (iii) the HHV-6 systematic gene name (where known), (iv) the protein size, and (v) the HIV-1 promoter elements required for transactivation. Also shown are the unique segment and the left and right direct repeat regions (DRL and DRR, respectively). Adapted from reference 87 with permission of the publisher. (B) Restriction map of HHV-6 strain U1102 SalI-L showing the locations and sizes of the ORFs (178). The hatched rectangle represents the junctional telomeric repeats ([TAACCC]43) which divide the left direct repeat (DRL) (heavy line) from the unique segment (light line). Depicted below the ORF-1 is the truncated peptide translated from the ORF-1–TTL172 mutant construct. Adapted from reference 86 with permission of the publisher.