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Validation of ADAMTS9 as a direct target gene of miR-93-5p. Note: (a) miR-93-5p mimic and miR-93-5p inhibitor were transfected into OA chondrocytes to overexpress and knockdown miR-93-5p, respectively. (b) The interaction between ADAMTS9 and miR-93-5p was detected with dual luciferase reporter gene assay. (c) RT-qPCR was performed to detect the expression of pro-inflammatory factors (IL-6, IL-1β, TNF-α) and iNOS. *P < 0.05; **P < 0.01; ***P < 0.001.
