Table 1.
Virulence Factor | C. albicans | C. auris | C. haemulonii | C. duobushaemulonii | E- value* | Similarity (%)* |
---|---|---|---|---|---|---|
Adhesins | Als1 | CJI96_0005138 | CXQ85_004547 | CXQ87_001667 | 5e−45 | 52 |
Als5 | CJJ09_005316 | CXQ85_004547 | CXQ87_004268 | 1e−34 | 49 | |
Eap1 | No found | No found | No found | - | - | |
Ecm33 | CJI96_0003481 | CXQ85_001305 | CXQ87_002344 | 8e−109 | 74 | |
Hwp1 | No found | No found | No found | - | - | |
Iff4 | FDK38_004751 | CA3LBN_002465 | CXQ87_001664 | 3e−35 | 54 | |
Int1 | CJI97_004446 | CXQ85_004340 | CXQ87_001341 | 0 | 59 | |
Mp65 | CJI97_003871 | CA3LBN_003990 | CXQ87_004408 | 7e−128 | 82 | |
Mnt1 | CJI97_002568 | CA3LBN_000314 | CXQ87_000344 | 0 | 79 | |
Biofilm formation | Bcr1 | CJI97_004038 | CXQ85_004690 | CXQ87_002954 | 4e−38 | 89 |
Brg1 | FDK38_005190 | FT662_01339 | CXQ87_004952 | 1e−46 | 86 | |
Efg1 | QG37_02326 | CXQ85_002192 | CXQ87_000637 | 8e−82 | 96 | |
Hsp90 | CJI97_005002 | CXQ85_001622 | CXQ87_003642 | 0 | 95 | |
Ndt80 | QG37_08107 | CXQ85_000348 | CXQ87_003781 | 4e−104 | 64 | |
Rob1 | CJI96_0002486 | CXQ85_004697 | CXQ87_001650 | 4e−18 | 59 | |
Csr1 | QG37_01438 | FT662_04426 | CXQ87_003974 | 1e−137 | 54 | |
Dimorphism | Cph1 | QG37_02170 | CA3LBN_000777 | CXQ87_000890 | 5e−113 | 64 |
Hgc1 | CJI96_0003736 | CXQ85_001596 | CXQ87_003669 | 8e−98 | 65 | |
Nrg1 | CJI96_0004799 | CA3LBN_003361 | CXQ87_004169 | 6e−32 | 84 | |
Tup1 | CJI96_0003109 | CXQ85_002914 | CXQ87_003349 | 0 | 88 | |
Hydrolytic enzymes | Lip5,6 | CJI97_004237 | CXQ85_004470 CXQ85_005044 |
CXQ87_004175 CXQ87_004891 |
1e−131 | 66 |
Lip7 | QG37_04164 | CA3LBN_003355 | CXQ87_004175 | 6e−82 | 57 | |
Lip8 | CJJ07_002584 | CXQ85_005044 | CXQ87_004175 | 6e−120 | 64 | |
Sap1-5 | CJI97_001086 QG37_06522 FDK38_003693 |
CA3LBN_003236 | CXQ87_003599 | 6e−65 | 50 | |
Plb1 | CJI96_0001982 | CA3LBN_002387 | CXQ87_001754 | 7e−44 | 64 | |
Plb2 | FDK38_001316 | CXQ85_003530 | CXQ87_001754 | 0 | 67 | |
Plb3 | B9J08_003621 | CA3LBN_002270 | CXQ87_001881 | 0 | 73 | |
Immune evasion | Hgt1 | CJI97_005618 | CA3LBN_003269 | CXQ87_004697 | 0 | 81 |
Msb2 | CJJ09_002134 | CXQ85_000170 | CXQ87_002736 | 9e−61 | 59 | |
Pra1 | CJI96_0000822 | CXQ85_002340 | CXQ87_000786 | 4e−82 | 65 | |
Thermotolerance | Hsp60 | CA7LBN_000129 | CXQ85_004696 | CXQ87_001649 | 0 | 96 |
Hsp104 | CJJ07_002319 | CA3LBN_001741 | CXQ87_002478 | 0 | 94 | |
Ssa1/Hsp70 | FDK38_001195 | CXQ85_001344 | CXQ87_001126 | 0 | 94 |
Notes: *A BlastP analysis was performed using the database of The National Center for Biotechnology (https://www.ncbi.nlm.nih.gov/) using the C. albicans proteins as a query.