Table 3. Clinical Data and Their Changes Compared to the Baseline Values for Glycemic Profile of Participants After 8 Weeks of Randomized Treatment.
| CBD/Δ9-THC (10:1) (n = 24) | Placebo (n = 22) | CBD/Δ9-THC (10:1) vs Placebo P-Value | |||||
|---|---|---|---|---|---|---|---|
| After 2 Months | Change from Baseline, % | P-Value | After 2 Months | Change from Baseline, % | P-Value | ||
| Fasting glucose, mg/dL | 133.7 ± 9.7 | -7.5 | 0.0125 | 140.0 ± 9.8 | +0.5 | 0.84 | < 0.001 |
| Hb A1C , % | 7.8 ± 0.24 | -8.5 | < 0.001 | 7.35 ± 0.15 | +1.3 | 0.075 | < 0.001 |
| Baseline insulin mIU/L | 22.53 | -16.6 | < 0.001 | 25.67 ± 12.2 | +5.7 | 0.59 | < 0.001 |
| HOMA2-IR | 3.12 ± 0.12 | -17.94 | < 0.001 | 3.57 ± 0.13 | +5.89 | < 0.001 | < 0.001 |
| HOMA2β | 93.8 ± 6.1 | +2.78 | 0.3565 | 95.4 ± 9.2 | +3 | 0.30 | 0.7 |