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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Bioessays. 2023 Feb 15;45(4):e2200191. doi: 10.1002/bies.202200191

Figure 2. How thresholds affect performance metrics.

Figure 2.

A. A hypothetical experiment using a threshold to optimize the accuracy (89%). B. A hypothetical experiment using a threshold typical of a screen where the experiment focuses on capturing positives, but also captures a significant portion of negatives, labeled FP. C A hypothetical experiment where the dynamic range of the response variable is increased to separate positives and negatives.