Table 3.
Exposure quartile | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Serum n-6 PUFA | 1 (n 421) | 95 % CI | 2 (n 421) | 95 % CI | 3 (n 422) | 95 % CI | 4 (n 421) | 95 % CI | P for trend § | Mean difference between the highest and the lowest quartile | 95 % CI |
Total n-6 PUFA (%) | 13·99–30·13 | 30·14–33·29 | 33·30–36·17 | 36·18–47·25 | |||||||
Model 1 † | 2463 | 2412, 2515 | 2537 | 2485, 2588 | 2559 | 2508, 2611 | 2615 | 2563, 2667 | <0·001 | 152 | 79, 225 |
Model 2‡ | 2459 | 2409, 2509 | 2533 | 2485, 2582 | 2566 | 2517, 2614 | 2616 | 2566, 2666 | <0·001 | 157 | 85, 230 |
LA (%) | 10·30–23·82 | 23·83–26·70 | 26·71–29·63 | 29·64–41·30 | |||||||
Model 1 | 2489 | 2437, 2540 | 2517 | 2465, 2568 | 2562 | 2511, 2614 | 2606 | 2555, 2659 | 0·001 | 118 | 45, 191 |
Model 2 | 2476 | 2425, 2526 | 2510 | 2461, 2558 | 2575 | 2527, 2624 | 2613 | 2563, 2664 | <0·001 | 138 | 64, 212 |
GLA (%) | 0·06–0·20 | 0·21–0·27 | 0·28–0·35 | 0·36–0·87 | |||||||
Model 1 | 2572 | 2514, 2613) | 2542 | 2484, 2599 | 2599 | 2542, 2655 | 2558 | 2500, 2616 | 0·98 | –15 | –97, 67 |
Model 2 | 2477 | 2522, 2632 | 2546 | 2493, 2600 | 2581 | 2527, 2634 | 2567 | 2513, 2622 | 0·97 | –10 | –88, 68 |
DGLA (%) | 0·57–1·15 | 1·16–1·33 | 1·34–1·50 | 1·51–3·02 | |||||||
Model 1 | 2514 | 2456, 2572 | 2498 | 2440, 2555 | 2608 | 2552, 2664 | 2650 | 2593, 2708 | <0·001 | 136 | 54, 218 |
Model 2 | 2502 | 2447, 2558 | 2519 | 2465, 2572 | 2604 | 2551, 2656 | 2645 | 2590, 2700 | <0·001 | 143 | 63, 223 |
AA (%) | 1·68, 4·14 | 4·15–4·76 | 4·77–5·44 | 5·45–9·21 | |||||||
Model 1 | 2495 | 2434, 2556 | 2550 | 2493, 2607 | 2613 | 2556, 2671 | 2603 | 2548, 2658 | < 0·001 | 108 | 26, 190 |
Model 2 | 2501 | 2450, 2553 | 2541 | 2492, 2590 | 2574 | 2526, 2622 | 2558 | 2506, 2610 | 0·11 | 57 | –20, 134 |
LA, linoleic acid; GLA, γ-linolenic acid; DGLA, dihomo-γ-linolenic acid and AA, arachidonic acid.
Values are means (95 % CI). Data were analysed with ANCOVA.
Model 1: adjusted for age and examination years.
Model 2: adjusted for model 1 plus BMI, smoking status, leisure-time physical activity, alcohol intake, use of antihypertensive medication, education, income and serum long-chain n-3 PUFA concentrations.
P for trend refers to the linear trend across the fatty acid quartiles.