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. 2022 Dec 24;270(4):2048–2058. doi: 10.1007/s00415-022-11529-6

Table 3.

P values for pairwise comparison of on-study annualized relapse rate

White (ARR 0.24) AQP4 + White (ARR 0.21) Black (ARR 0.24) AQP4 + Black (ARR 0.22) Asian (ARR 0.11) AQP4 + Asian (ARR 0.07) Latino (ARR 0.30) AQP4 + Latino (ARR 0.34)
Race only
 White (ARR 0.24) Ref. 0.912 0.024 0.392
 AQP4 + White (ARR 0.21) Ref. 0.707 0.008 0.046
 Black (ARR 0.24) Ref. 0.041 0.405
 AQP4 + Black (ARR 0.22) Ref. 0.007 0.131
 Asian (ARR 0.11) Ref. 0.013
 AQP4 + Asian (ARR 0.07) Ref. 0.001
 Latino (ARR 0.30) Ref.
 AQP4 + Latino (ARR 0.34) Ref.
Female only White (ARR 0.26) AQP4 + White (ARR 0.21) Black (ARR 0.19) AQP4 + Black (ARR 0.20) Asian (ARR 0.07) AQP4 + Asian (ARR 0.08) Latino (ARR 0.31) AQP4 + Latino (ARR 0.35)
 White (ARR 0.26) Ref. 0.197 0.003 0.483
 AQP4 + White (ARR 0.21) Ref. 0.778 0.020 0.040
 Black (ARR 0.19) Ref. 0.030 0.123
 AQP4 + Black (ARR 0.20) Ref. 0.036 0.042
 Asian (ARR 0.07) Ref. 0.003
 AQP4 + Asian (ARR 0.08) Ref. 0.001
 Latino (ARR 0.31) Ref.
 AQP4 + Latino (ARR 0.35) Ref.
Male only White (ARR 0.15) AQP4 + White (ARR 0.18) Black (ARR 0.65) AQP4 + Black (ARR 0.52) Asian (ARR 0.29) AQP4 + Asian (ARR 0.00) Latino (ARR 0.22) AQP4 + Latino (ARR 0.14)
 White (ARR 0.15) Ref. 0.006 0.317 0.651
 AQP4 + White (ARR 0.18) Ref. 0.062 1.000 0.813
 Black (ARR 0.65) Ref. 0.272 0.241
 AQP4 + Black (ARR 0.52) Ref. 1.000 0.276
 Asian (ARR 0.29) Ref. 0.785
 AQP4 + Asian (ARR 0.00) Ref. 1.000
 Latino (ARR 0.22) Ref.
 AQP4 + Latino (ARR 0.14) Ref.

On-study relapses included those that began up to 90 days before study start

AQP4 + , anti–aquaporin 4 seropositive; ARR, annualized relapse rate

Bold, significant difference at the P < 0.05 level