Table 1.
Demographic and clinical characteristics of health control, AP-nonARDS, and AP-ARDS group.
| CONTROL (n=20) |
AP-nonARDS (n=39) |
AP-ARDS (n=26) |
P value (AP-nonARDS vs AP-ARDS) | |
|---|---|---|---|---|
| Age (years), mean ± SD | 37.20 ± 12.00 | 44.15 ± 15.02 | 48.69 ± 13.99 | 0.135 |
| Male, n (%) | 11(55.00) | 17(43.59) | 17(65.38) | 0.085 |
| BMI (kg/m2), mean ± SD | 22.80 ± 2.89 | 26.19 ± 3.63 | 26.48 ± 3.88 | 0.794 |
| Smoking, n (%) | 9(23.07) | 9(34.62) | 0.308 | |
| Drinking, n (%) | 9(23.07) | 7(26.92) | 0.724 | |
| Comorbid abnormalities, n (%) | ||||
| Hypertension | 10(25.64) | 13(50.00) | 0.044 | |
| Diabetes | 9 (23.07) | 8(30.77) | 0.489 | |
| Fatty liver | 27(69.23) | 16(61.54) | 0.521 | |
| Etiology, n (%) | 0.538 | |||
| Biliary | 18(46.15) | 9(34.62) | ||
| Hypertriglyceridemia | 17(43.59) | 15(57.69) | ||
| Alcohol consumption | 4(10.26) | 2(7.69) | ||
| Disease severity, n (%) | <0.001 | |||
| MAP | 21(53.85) | 0(0.00) | ||
| MSAP | 17(43.59) | 7(26.92) | ||
| SAP | 1(2.56) | 19(73.08) | ||
| APACHE II, mean ± SD | 3.13 ± 2.25 | 9.96 ± 4.17 | <0.001 | |
| SOFA score, mean ± SD; median (IQR) | 0.54 ± 0.64; 0.00 (0.00,1.00) |
6.12 ± 4.09; 4.00(3.00, 7.25) |
<0.001 | |
| Balthazar score E, mean ± SD | 2.90 ± 1.02 | 4.04 ± 0.72 | <0.001 | |
| Local complications, n (%) | ||||
| Acute peripancreatic fluid collection (APFC) | 14(35.90) | 24(92.31) | <0.001 | |
| Pancreatic pseudocyst (PP) | 3(7.69) | 2(7.69) | >0.999 | |
| Acute necrotic collection (ANC) | 2(5.13) | 12(46.15) | <0.001 | |
| Walled off necrosis (WON) | 0(0.00) | 2(7.69) | 0.079 | |
| Infected necrosis | 0(0.00) | 8(30.77) | 0.001 | |
| Systematic complication, n (%) | ||||
| Systemic inflammatory response syndrome (SIRS) | 13(33.33) | 22(84.62) | <0.001 | |
| Acute kidney injury | 1(2.56) | 12(46.15) | <0.001 | |
| Shock | 0(0.00) | 10(38.46) | <0.001 | |
| Liver damage | 1(2.56) | 11(42.31) | <0.001 | |
| Myocardial injury | 1(2.56) | 6(23.08) | 0.009 | |
| Sepsis | 1(2.56) | 14(53.85) | <0.001 | |
| Abdominal compartment syndrome (ACS) | 1(2.56) | 7(26.92) | 0.003 | |
| Bowel obstruction | 3(7.69) | 7(26.92) | 0.035 | |
| Outcome | ||||
| Organ failure, n (%) | 4(10.26) | 26 (100.0) | <0.001 | |
| Organ failure duration (h), mean ± SD; median (IQR) | 2.59 ± 8.30; 0.00(0.00,0.00) |
164.65 ± 159.85; 85.00(41.50,276.00) |
<0.001 | |
| ICU, n (%) | 0(0.00) | 19(73.08) | <0.001 | |
| ICU stay (days), mean ± SD; | 0.00 ± 0.00 | 7.15 ± 6.59 | <0.001 | |
| Hospital stay (days), mean ± SD | 8.26 ± 6.65 | 23.04 ± 11.52 | <0.001 | |
| Death, n (%) | 0(0.00) | 1(3.85) | 0.217 | |