Example of the relationship among haplotypes in ECH regions
(A) The core 900 kb region (where the ECH frequency is at least 90% of its peak value) of the longest and most frequent ECH. The left side of each figure is a UPGMA tree with the x axis representing Jukes-Cantor-corrected sequence distances between male haplotypes. The individual haplotypes are shown as horizontal lines on the right with the x axis in hg19 Mb coordinates. Haplotypes are color coded according to geographical region. The ancient Ust’-Ishim individual is marked with gray. Vertical black bars on each haplotype represents non-reference SNPs.
(B) For comparison, a 900 kb region where no ECHs were identified (see Figure S10 for visualizations of all ECHs).