TABLE 2.
Expression pattern of Six4 determined by X-Gal staining of heterozygotes
| Stage | Tissuea |
|---|---|
| Embryonic | |
| E8.5 | Surface ectoderm outside the neural folds, somites, presomitic mesoderm |
| E9.5 | Nasal and otic placodes, cranial ganglia, branchial arches, somites (dermamyotomes and sclerotomes), AER |
| E10.5–11.5 | Nasal pits, otic vesicles, cranial ganglia (V, VII–XI), dorsal root ganglia, branchial arches, somites, myotomes, limb mesenchyme, AER, notochord, mesonephros |
| E12.5–E13.5 | Skeletal muscles, mesenchyme in limbs and digits, nasal epithelium, inner ear |
| Adult | Skeletal muscle, nasal epithelium, cochlea, parathyroid, salivary gland |
a
AER, apical ectodermal ridges.