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. 2023 Feb 27;82(4):283–295. doi: 10.1093/jnen/nlad015

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© The Author(s) 2023. Published by Oxford University Press on behalf of American Association of Neuropathologists, Inc. All rights reserved. For permissions, please email: journals.permissions@oup.com

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Figure 1. — Clinical characteristics and neuropathologic features of SARS-CoV-2 Delta, Omicron, and non-Delta/non-Omicron variants. Heat maps from left to right show clinical details including patient age, sex, SARS-CoV-2 variant, vaccination status, comorbidities, and duration of illness, neuropathological features including hypoxia-ischemic changes, ischemic infarct, and cerebral hemorrhage, virus nucleocapsid and spike immunohistochemistry, spike RNA in situ hybridization, and RT-qPCR using probes for the nucleocapsid (N1) gene target. CKD, chronic kidney disease; CVD, cardiovascular disease; DM, diabetes mellitus; HTN, hypertension; IHC, immunohistochemistry; ISH, in situ hybridization; NDO, non-Delta/non-Omicron; RT-qPCR, real-time quantitative polymerase chain reaction; N1, nucleocapsid gene (based on the US CDC N1 probes).