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. 2023 Mar 1;26(4):106302. doi: 10.1016/j.isci.2023.106302

Figure 6.

Figure 6

Subclusters of cardiac fibroblasts and functional screening

(A) UMAP of cardiac fibroblasts showing three clusters, F1, F2, and F3.

(B) Individual UMAPs showing the fibroblasts from each tissue configuration.

(C) Bar graph on the fraction of each tissue configuration type contributing to the clusters.

(D) Violin plots showing normalised expression of highly expressed fibroblast genes. Black dots indicate the mean values.

(E) Violin plots showing normalised expression levels of ACTA2, COL1A1, COL1A2, DCN, and FN1 of tissue types in fibroblasts. Black dots indicate the mean values.

(F) Bar plot showing adjusted p value (-log10) of the enriched GO terms calculated for the top DEGs between CS and other configurations hvCAS, hvCTS, and hvCOC.