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. Author manuscript; available in PMC: 2023 Oct 4.
Published in final edited form as: J Am Coll Cardiol. 2022 Oct 4;80(14):1287–1298. doi: 10.1016/j.jacc.2022.07.027

FIGURE 4. Cumulative Incidence of MACE in Highest vs Lowest LPA-GRS Quintiles.

FIGURE 4

We calculated an LPA-GRS using variants listed in Supplemental Table 1. We estimated the cumulative incidence of MACE between participants in the highest (red line) vs lowest (blue line) quintiles of the LPA-GRS distribution. (A) In the placebo arm, a higher cumulative incidence of MACE was observed in the high vs low LPA-GRS quintile. (B) However, in the aspirin arm, a lower cumulative incidence of MACE was observed in the highest vs lowest LPA-GRS quintile. Lp(a) = lipoprotein(a); other abbreviations as in Figure 3.