TABLE 1.
Demographic and clinical information for participants included in initial performance analyses as well as analyses focused on practice effects.
| Initial performance subset (n = 4287) | Practice effect subset (n = 4141) | A+ initial performance subset with tau data (n = 354) | A+ practice effect subset with tau data (n = 343) | |
|---|---|---|---|---|
| Age, mean (SD) | 71.25 (4.648) | 71.23 (4.643) | 71.93 (4.706) | 71.95 (4.721) |
| Sex, n (%) | ||||
| Male | 1715 (40%) | 1663 (40%) | 142 (40%) | 137 (40%) |
| Female | 2572 (60%) | 2478 (60%) | 212 (60%) | 206 (60%) |
| Education, mean (SD) | 16.61 (2.844) | 16.61 (2.853) | 16.23 (2.841) | 16.23 (2.841) |
| Race, n (%) | ||||
| White | 4003 (93%) | 3869 (94%) | 338 (95%) | 327 (95%) |
| Asian | 68 (2%) | 65 (2%) | 2 (1%) | 2 (1%) |
| Black | 155 (4%) | 148 (4%) | 9 (3%) | 9 (3%) |
| Other | 61 (1%) | 59 (1%) | 5 (1%) | 5 (1%) |
| Ethnicity, n (%) | ||||
| Hispanic or Latino | 136 (3%) | 132 (3%) | 9 (3%) | 8 (2%) |
| Not Hispanic or Latino | 4117 (96%) | 3976 (96%) | 338 (95%) | 329 (96%) |
| Unknown or Not Reported | 34 (1%) | 33 (1%) | 7 (2%) | 6 (2%) |
| APOE, n (%) | ||||
| E2/E2 | 25 (1%) | 24 (1%) | 1 (0%) | 1 (0%) |
| E2/E3 | 427 (10%) | 414 (10%) | 15 (4%) | 15 (4%) |
| E2/E4 | 110 (3%) | 105 (3%) | 13 (4%) | 12 (3%) |
| E3/E3 | 2296 (54%) | 2223 (54%) | 129 (36%) | 126 (37%) |
| E3/E4 | 1252 (29%) | 1209 (29%) | 168 (47%) | 163 (48%) |
| E4/E4 | 137 (3%) | 134 (3%) | 24 (7%) | 24 (7%) |
| Unknown | 40 (0.9%) | 32 (0.8%) | 4 (1.1%) | 2 (0.6%) |
| Amyloid Status, n (%) | ||||
| A− | 3017 (70%) | 2906 (70%) | 0 (0%) | 0 (0%) |
| A+ | 1270 (30%) | 1235 (30%) | 354 (100%) | 343 (100%) |
| PACC, mean (SD) | 0.008 (2.530) | −0.003 (2.530) | −0.591 (2.785) | −0.576 (2.771) |
| GDS, mean (SD) | 1.005 (1.445) | 0.998 (1.429) | 0.983 (1.275) | 0.980 (1.271) |
| STAI, mean (SD) | 9.917 (3.123) | 9.887 (3.101) | 10.150 (3.056) | 10.130 (3.062) |
Abbreviations: A−, normal amyloid; A+, abnormal amyloid; C3, computerized cognitive composite; GDS, Geriatric Depression Scale; PACC, Preclinical Alzheimer's Cognitive Composite; STAI, State‐Trait Anxiety Inventory.