Table 1.

Semi-structured interview guide.^*

1. So, to start, where did you first hear about the COB-MS study? 2. Can you recall what initially piqued your interest in taking part in this research? 3. We are interested in learning more about the decision-making process regarding participation in our research study. We currently don’t know about how people go about making the decision regarding whether they want to take part in research, so that’s why we’re asking to get some insight into this from you; so, would you mind helping us understand how you came about making the decision to not participate in the COB-MS programme? a. . . .and what would you say were the main reasons for choosing not to participate? 4. Was this an easy decision for you? a. Did this decision take time to make? 5. Can you recall getting a chance to read through the information sheet? a. Was there anything in the information sheet that concerned you? b. Were there any particular elements of what was presented in the information sheet that did make you consider taking part? 6. What change or changes would need to have been made for you to participate? 7. Do you have any experience of taking part in research before? a. (Yes) Can you tell me a bit about it? 8. Can you tell me how you felt about the possibility of taking part in this research study before declining? 9. Based on the information provided to you, what did you think of the appropriateness and acceptability of the COB-MS programme with respect to your situation? 10. Did you have any concerns about your ability to participate in the programme? 11. Can you tell me how you feel about participating in research now?

^*The PPI panel was asked to comment, discuss and/or elaborate on the interview responses to these semi-structured questions.