TABLE 2.

The relationship of quantification (mean ± SEM) of NOTCH1 and SF3B1 mutations with disease profile status

Parameters	Statistics	Molecular study
		NOTCH1 Ex34		SF3B1 Ex14‐16
		Mutation	Wild type	Mutation	Wild type
Age (Year)	Mean	62.25	57.83	55.11	59.26
	SEM	5.19	2.24	4.89	2.26
	p‐value	.439		.445
WBC count (×103/μl)	Mean	37.87	19.7	31	20.74
	Mean (LR)	3.63	2.98	3.43	3.03
	SEM	0.32	0.19	0.34	0.19
	p‐value	.109·		.332
Lymphocyte count (×103/μl)	Mean	53.17	55.58	68.67	52.31
	Mean (LR)	3.97	4.01	4.22	3.95
	SEM	0.46	0.19	0.38	0.2
	p‐value	.930		.546
Hb level (g/dL)	Mean	12.48	13.61	13.27	13.46
	Mean (LR)	2.52	2.61	2.58	2.6
	SEM	0.07	0.02	0.06	0.03
	p‐value	.261		.847
Hct (%)	Mean	37.55	40.7	39.77	40.28
	SEM	2.66	1.17	2.54	1.2
	p‐value	.284		.859
Plt count (×103/μl)	Mean	152	170.85	189.77	162.82
	Mean (LR)	5.02	5.14	5.24	5.09
	SEM	0.16	0.06	0.14	0.07
	p‐value	.517		.345
Cell with CLL phenotype, %CD38	Mean	62.25	57.83	55.11	59.26
	SEM	5.19	2.24	4.89	2.26
	p‐value	.439		.445
Cell with aCLL phenotype, %CD38 ≥ 30%	Mean	57.6	74.87	81	64.4
	SEM	6.58	5.2	8.98	4.93
	p‐value	.064 ·		.133 ·

Abbreviations: LR, logistic regression; SEM, standard error of the mean; TS(·), tendency to significant.