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. 2023 Mar 20;12:32. doi: 10.1186/s40164-023-00396-0

Table 1.

Patient and treatment characteristics

Deidentified number Gender Race Ethnicity Age at diagnosis B-SX at DX Initial stage IPI Bulky  > 10 cm 1st line of therapy At least one relapse 2nd line of therapy 3rd line of therapy 4th line of therapy FU in
months
Status at last FU
PML01 Male white not Hispanic 46 No II 1 Yes 6xDA-R-EPOCH No 18 Alive
PML02 Female Asian not Hispanic 30 No II 1 Yes 6xDA-R-EPOCH No 32 Alive
PML03 Male white Hispanic 36 No IV 2 No 6xDA-R-EPOCH No 21 Alive
PML04 Male white not Hispanic 54 No IV 2 Yes 6xDA-R-EPOCH Yes 3xR-ICE, ASCT and XRT 65 Alive
PML05 Male American Indian not Hispanic 38 No I 1 Yes 6xDA-R-EPOCH No 26 Alive
PML06 Female Hawaiian/Pacific Islander Hispanic 29 Yes II 1 Yes 6xDA-R-EPOCH Yes 1 × R-DHAP 1xR-ICE, Liso-cel 29 Alive
PML07 Male white NA 30 Yes III 1 Yes 1xABVD + 6xDA-R-EPOCH Yes 3xR-DHAP, then ASCT Selinexor and Rituximab Rituximab + fractionated Cyclophosphamide 15 Dead
PML08 Female white not Hispanic 24 Yes IV 2 No 6xDA-R-EPOCH No 38 Alive
PML09 Female white not Hispanic 50 Yes IV 3 Yes 6xDA-R-EPOCH Yes 1xR-DHAP Tisa-cel 7xPembrolizumab + XRT 31 Alive
PML10 Male white not Hispanic 22 No II 0 No 4xDA-R-EPOCH No 35 Alive
PML11 Male white not Hispanic 38 Yes III 1 No

1xR-CHOP + Len,

 + 5xDA-R-EPOCH

No 37 Alive
PML12 Female white not Hispanic 28 No IV 1 No 5xDA-R-EPOCH Yes Axi-cel 8xPembrolizumab, ASCT and XRT 57 Alive

ABVD: doxorubicin hydrochloride, bleomycin sulfate, vinblastine sulfate, and dacarbazine; ASCT: autologous stem cell transplantation; axi-cel: axicabtagene ciloleucel; DA-R-EPOCH: dose-adjusted rituximab, etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin; DX: diagnosis; FU: follow-up; IPI: International Prognostic Index; Len: lenalidomide; Liso-cel: lisocabtagene maraleucel; NA: not available; R-DHAP: rituximab, cytosine arabinoside, dexamethasone; R-ICE: rituximab, ifosfamide, carboplatin, and etoposide; SX: symptoms;Tisa-cel: tisagenlecleucel; x: cycles; XRT: radiotherapy of the mediastinum