Skip to main content
. Author manuscript; available in PMC: 2023 Mar 20.
Published in final edited form as: Ann Rheum Dis. 2016 Oct 18;76(4):731–739. doi: 10.1136/annrheumdis-2016-209206

Figure 5. Joint myeloid cell recruitment and M1 macrophage polarization are upregulated in obese TLR4 arthritic mice compared to lean controls.

Figure 5.

A. STs from TLR4 arthritic mice (72h) on RD and HFD were immunostained with anti-F4/80 antibody (orig. mag. x 200) and B. macrophage staining was quantified on a 0-5 scale, n=7. C. STs from TLR4 arthritic mice (72h) on RD and HFD were immunostained with anti-iNOS and anti-Arginase antibodies (orig. mag. x 200) and D. positive staining was quantified on a 0-5 scale, n=7. E. Ankle homogenates harvested following 72h of LPS i.a. injection from mice fed on RD and HFD, were Western blotted for iNOS and Arginase expression or actin equal loading, n=5. Values are mean ± SE. * indicates p<0.05.