Figure 6.

Identification of proteins with potentially altered levels of expression. A Qiagen RT² Profiler PCR Array was employed to determine the altered transcription of a set of 96 human NF-κB genes involved in signaling pathways. These genes were studied in the presence of wild-type NF-κB and six mutants. Each of the mutants contained a stoichiometrically phosphorylated tyrosine, all differing by their position. The genes exhibited different transcription levels for each individual NF-κB. The letter M preceding the label for each phosphorylated NF-κB protein denotes “mutant”.