Table 1.

Demographic and neuropathological characteristics by braak stage

	Braak 0 – II (n = 66)	Braak III (n = 75)	p
Age at death (years)	82.25 ± 6.56	86.43 ± 5.70	<0.001
Sex (M/F)	41/25	37/38	0.13
Education (y)	18.27 ± 4.03	17.83 ± 3.74	0.50
APOE ε4 (Carrier/Non-Carrier)	11/54	10/64	0.58
Clinical diagnosis (NCI/MCI/AD)	39/15/12	33/18/24	0.12
Postmortem interval (hours)	7.01 ± 4.07	6.03 ± 3.77	0.18
Duration between last clinical	0.73 ± 0.64	0.64 ± 0.49	0.35
assessment and autopsy (y)
Brain weight at autopsy (g)	1,256.28 ± 151.55	1,222.82 ± 133.93	0.17
Cerebral amyloid angiopathy	32/29	50/18	0.01
(present/absent)
Neuritic plaque count	0 (0–11)	10 (0–37)	<0.001
Diffuse plaque count	4 (0–38)	21.50 (0–60)	0.23

Mean ± standard deviation; median (25th %ile, 75th %ile).