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. Author manuscript; available in PMC: 2023 Jul 16.
Published in final edited form as: Nat Cardiovasc Res. 2023 Jan 16;2:144–158. doi: 10.1038/s44161-022-00206-6

Extended Data Fig. 10. Association of CHIP and Large CHIP (variant allele fraction>10%) with PAD in the UKB (N=37,657).

Extended Data Fig. 10.

under 1) unadjusted, 2) sparsely adjusted, and 3) fully adjusted models, where sparsely adjusted refers to the following covariates: age, age2, sex, smoking status, Townsend deprivation index, and the first ten principal components of genetic ancestry, and the fully adjusted model additionally includes normalized BMI, prevalent hypertension, hyperlipidemia, and type 2 diabetes as covariates. Given the minimal difference between the sparsely adjusted and fully adjusted model, the sparsely adjusted model was moved forward for use in analysis. Error bars are centered at the HR and show the 95% CI for estimates.