Skip to main content
. Author manuscript; available in PMC: 2023 Jul 16.
Published in final edited form as: Nat Cardiovasc Res. 2023 Jan 16;2:144–158. doi: 10.1038/s44161-022-00206-6

Extended Data Figure 2. Association of CHIP (a) and VAF (b) with incident hematologic malignancy among individuals without prevalent hematological malignancy in the UK Biobank (n=37,657).

Extended Data Figure 2.

Associations are adjusted for age, age2, sex, smoking status, Townsend deprivation index, and the first ten principal components of genetic ancestry. (a) Error bars are centered at the HR and show the 95% CI for estimates. (b) Error bands reflect the standard error of a generalized binomial additive model with integrated smoothness fit to the data. CHIP = clonal hematopoiesis of indeterminate potential; VAF = variant allele fraction